ANALYTICAL METHOD DEVELOPMENT, VALIDATION, AND ASSAY OF BETAMETASONE DIPROPIONATE CREAM BY HPLC METHOD

Analytical Method Development and Validation of Estimation Method for Sotalol Hydrochloride Tablets by Using Rp-hplc

The present investigation describes about a simple, economic, selective, accurate, precise Reverse phase High performance liquid chromatographic method for the estimation of Sotalol Hydrochloride in pharmaceutical dosage forms. Sotalol Hydrochloride was well eluted using a C18 column of dimension 100 × 4.6, 5μm and Mobile phase consisting of Acetonitrile: 20 mM Ammonium acetate buffer (pH-6): M...

Development and validation of RP HPLC method for determination of betamethasone dipropionate in gingival crevicular fluid.

Abstract A simple RP HPLC method for quantification of betamethasone dipropionate (BDP) in gingival crevicular fluid (GCF) has been developed and validated. GCF represents a valuable matrix for therapeutic monitoring of drugs used in the treatment of periodontal disease. The proposed method involves single step extraction for sample preparation. The calibration curve for BDP was linear over the...

Analytical method development and validation for assay of Diosmin and Hesperidin in combined tablet dosage form by RP- HPLC

The combination of Diosmin and Hesperidin can be used as capillary stabilizing and antihemorrhoidal agent. A rapid, simple, precise and cost effective and reversed-phase high performance liquid chromatography (RP-HPLC) method has been developed and validated for the simultaneous determination of Diosmin and Hesperidin in pharmaceutical formulations. Separation of both Diosmin and Hesperidin was...

development and validation of a new hplc analytical method for the quality control of clindamycin capsules

Stability Indicating Analytical Method Development and Validation of Lafutidine in Tablet Dosage Form by Rp- Hplc

Objectives: To perform stability indicating analytical method development and validation of Lafutidine in tablet dosage form by reverse phase HPLC method. Materials and Methods: The method was developed employing isocratic RP-HPLC and validated for assay of Lafutidine in tablet dosage form. The method employs the use of a UV detector. Results: The developed assay method was found to be accurate...